Online economic evaluation

  • Projects, Health Technology Assessment Projects and Health Economics
  • Concluded
Economic Evaluation of the Use of Oxytocin in the Uniject™ Injection System Versus Standard Use in Ampoules for the Prevention of Postpartum Hemorrhage in the Active Management of the Third Stage of Labor in Latin America and the Caribbean

Postpartum hemorrhage (PPH) is one of the main causes of maternal death in the world and although the evidence is solid regarding the effectiveness of the use of oxytocin to prevent it, its use remains low. The Uniject (OiU) oxytocin pre-filled injection system has the potential to increase oxytocin use due to its ease of application but at a higher cost than the current vial use strategy.

The objective of this study is to evaluate the cost-effectiveness of replacing the use of oxytocin in ampoules with OiU in Latin America and the Caribbean. For this, an epidemiological model was built that estimated the impact of this intervention on health system costs, the incidence of PPH and quality-adjusted life years (QALYs or QALYs) in each country.

The results of the economic evaluation as well as the technical description of the model can be found here. This web platform was built as a tool to allow decision makers and researchers in each country to calibrate the economic model to their context, with the possibility of selecting new values ​​for the different parameters, thus obtaining results that are more adjusted to the local reality of their country. Country or region.

FUNDING SOURCE

This project was funded through a research contract between the Institute of Clinical and Health Effectiveness (IECS), the Pan American Health Organization (PAHO/WHO) and the Integrated Maternal and Child Health Program (MCHIP). from the United States Agency for International Development (USAID). USAID funding has been made possible by the generous support of the American people, under the terms of the Leader with Associates Cooperative Agreement GHS-A-00-08-00002-00. The contents are the responsibility of IECS and MCHIP and do not necessarily reflect the opinions of USAID, the United States Government, or PAHO.