Period: 2014-2015

Researchers

Poggio R, Elorriaga N, Gutierrez L, Irazola V, Rubinstein A.

Brief

As a consequence of the epidemiological transition suffered by low- and middle-income countries, unprudent diet has become the most prevalent cardiovascular risk factor, contributing significantly to the burden of cardiovascular disease worldwide. There are no data on the impact of our eating habits on cardiovascular risk factors in our population.

Objectives

Study objectives: 1) Identify the main dietary patterns in the adult population of Bariloche, Marcos Paz (Argentina), Temuco (Chile) and Canelones (Uruguay). 2) Investigate how the plasma levels of apolipoprotein (Apo) AI, Apo B, C-reactive protein (CRP), cholesterol and triglycerides vary in relation to these dietary patterns.

Summary

The CESCAS I study is a prospective observational study with a probabilistic and multistage sample of 7524 participants representative of the general population of 4 cities in Argentina, Chile and Uruguay. From this population, a sub-sample of 985 subjects without previous cardiovascular event or lipid-lowering treatment was randomly selected. Diet was determined using a 126-question food frequency questionnaire. A factor analysis by principal components was performed to derive the dietary patterns of our region and obtain their respective scores. Linear regression models were used to examine associations between Apo AI, Apo B, CRP, and other lipids (dependent variables) by quartile of dietary patterns score (independent variables).

Finance

Fogarty International Center. NIH

Derivative publications

Poggio R, Elorriaga N, Gutierrez L, Irazola V, Rubinstein A. Relationship among Dietary Patterns, Apolipoproteins, C Reactive Protein and Other Lipids in Adult Populations in Four Cities of the Southern Cone of Latin America. Circulation. 2014;129:AP271