Period: 2012-2017

Researchers: Jiang He, Vilma Irazola, Adolfo Rubinstein, Rosana Poggio, Andrea Beratarrechea, Pablo Gulayin, Analía Nejamis and Marilina Santero

Objectives:

The purpose of this study is to find out if a comprehensive plan that includes home health education, blood pressure self-monitoring, and health-related text messaging can reduce blood pressure levels in patients with hypertension and their families, compared to the usual care provided by their primary care physician.

• Net difference in SBP and DBP between the baseline determination and that recorded at 18 months in the intervention versus control group.
Secondary Objectives
• Proportion of controlled hypertensive patients (BP < 140/90 mmHg or < 130/80 mmHg if they have diabetes or chronic renal failure).
• Net difference in SBP and DBP between the baseline determination and that recorded at 18 months between hypertensive versus non-hypertensive patients.
• Cost effectiveness of the intervention.
• Net difference in weight and waist circumference.
• Changes in physical activity levels and diet.

Summary

Randomized intervention at the CAPS level of the public primary care network in collaboration with the Remediar+Networks Program of the Ministry of Health. A multifaceted intervention will be carried out for the prevention and control of HTN in hypertensive patients and their families by PC teams and health agents.

Finance

National Heart, Lung, and Blood Institute (NHLBI)/NIH

Derivative publications

Mills KT, Rubinstein A, Irazola V, Chen J, Beratarrechea A, Poggio R, et al. Comprehensive approach for hypertension control in low-income populations: Rationale and study design for the hypertension control program in Argentina. Am J Med Sci. 2014. 139-45. doi: 10.1097/MAJ.0000000000000298.

David Peiris, Simon R. Thompson2, Andrea Beratarrechea, María Kathia Cárdenas, Francisco Diez-Canseco, Jane Goudge, Joyce Gyamfi, Jemima Hoine Kamano, Vilma Irazola, Claire Johnson1, Andre P. Kengne, Ng Kien Keat9, J. Jaime Miranda, Sailesh Mohan, Barbara Mukasa11, Eleanor Ng, Robby Nieuwlaat, Olugbenga Ogedegbe6, Bruce Ovbiagele, Jacob Plange-Rhule, Devarsetty Praveen, Abdul Salam, Margaret Thorogood, Amanda G. Thrift, Rajesh Vedanthan, Salina P. Waddy, Jacqui Webster1, Ruth Webster , Karen Yeates, Khalid Yusoff, The GACD Hypertension Research Programme, Writing Group and Hypertension Research Program members. Behavior change strategies for reducing blood pressure-related disease burden: findings from a global implementation research program . Implementation Science 2015, 10:158, doi:10.1186/s13012-015-0331-0

W.Tobe, S., the Global Alliance for Chronic Diseases Hypertension Research Teams With the World Hypertension League (2016), The Global Alliance for Chronic Diseases Supports 15 Major Studies in Hypertension Prevention and Control in Low- and Middle-Income Countries. The Journal of Clinical Hypertension. doi:10.1111/jch.12835

Gulayin P, Irazola V, Lozada A, Chaparro M, Santero M, Gutierrez L, Poggio R, Beratarrechea A, Rubinstein A. Educational intervention to improve effectiveness in treatment and control of patients with high cardiovascular risk in low resource settings in Argentina: study protocol of a cluster randomized controlled trial. BMJ Open 2017;7:e014420. doi:10.1136/bmjopen-2016-014420